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Supports macronutrient metabolism and healthy skin

• Helps to maintain eyesight, skin, membranes and immune function
• Aids in the development and maintenance of bones, cartilage, teeth and gums
• Helps to prevent vitamin A, vitamin C and zinc deficiency
• Provides 9999 IU of vitamin A per daily dose
• Includes 498 mg of vitamin C and 24 mg of zinc per daily dose TAD+ is a multivitamin combination that helps the body metabolize macronutrients and maintain skin health. B vitamins help mediate hundreds of enzymatic reactions, including the formation of substrates for energy production in the Krebs cycle.

1 Zinc is highly present in the epidermis, and is needed for the proliferation of epidermal cells.2 Production of the retinol-binding protein, which transports vitamin A in cells, also depends on zinc.3 Vitamin A has three primary roles in the body: 1) help maintain the skin-s barrier function by increasing epidermal thickness and the number of glycosaminoglycans - polysaccharides that help hydrate the skin; 2) aid in the production of rhodopsin for sensing light, especially in low light environments; 3) stimulate the development of immune cells.4-6 Vitamin C contributes to the maintenance of bones, cartilage, teeth and gums through its role in the synthesis of collagen, the primary structural protein found in connective tissue.1 Vitamin C is also involved in wound healing, and helps to maintain good health by preventing free radical damage to DNA.1 NPN 80037033 08301 1. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier.
2. Schwartz, JR, Marsh, RG, Draelos, ZD. Zinc and Skin Health: Overview of Physiology and Pharmacology. Dermatol Surg. 2005; 31: 837-847.
3. Meunier, N, O-Connor, JM, Maiani, G, Cashman, KD, Secker, DL, Ferry, M, Coudray, C. Importance of zinc in the elderly: the ZENITH study. European Journal of Clinical Nutrition. 2005; 59(Suppl 2): S1-S4.
4. Ruhl, R. Effects of dietary retinoids and carotenoids on immune development. Proceedings of the Nutrition Society. 2007; 66: 458-469.
5. Al Tanoury, Z, Piskunov, A, Rochette-Egly, C. Vitamin A and retinoid signaling: genomic and nongenomic effects. Journal of Lipid Research. 2013; 54: 1761-1775.
6. Mukherjee, S, Date, A, Patravale, V, Korting, HC, Roeder, A, Weindl, G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging. 2006; 1(4): 327-348.

Key Ingredients: Adrenal, Licorice Root, Niacin, Pantothenic acid, Riboflavin, Spleen, Thiamine, Vitamin A, Vitamin B6, Vitamin C, Wild Yam Root, Zinc